The effectiveness and efficacy of Ophiocordyceps sinensis supplementation: A systematic review of randomized clinical trials on healthy humans

Jacob Welch, Reagan Kole, Sawyer Daniels
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Abstract

To critically assess the current evidence from randomized clinical trials performed on healthy human subjects for or against the effectiveness or efficacy of O. sinensis. Randomized studies testing the efficacy and effectiveness of O. sinensis against a placebo, conducted with healthy human subjects were included in this systematic review following The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA). Searches of PubMed, Library of Congress, JISC Library, Clinical Trials.gov, mRCT, Google Scholar, Embase, Web of Science, CINAHL, Medline, and Cochrane were conducted. Of the 4,308 potentially relevant articles, 29 full-text articles were reviewed, 7 of which were randomized trials conducted with healthx`y human subjects. All studies were classified as low risk with a total of 286 participants. Of the included studies, 5 noted significant pre/post intergroup differences. 5 results supported the utilization of O. sinensis as a powerful dietary supplement. The effect of supplementation with O. sinensis on aerobic performance could have implications in various athletic events. Insufficient reporting of the details of the O. sinensis preparation utilized is a common issue within included studies. Despite great efforts, there is a possibility not all relevant data was obtained.
补充冬虫夏草的有效性和疗效:对健康人随机临床试验的系统回顾
批判性地评估目前在健康人类受试者中进行的随机临床试验的证据,以支持或反对中华o.s sinensis的有效性。根据系统评价和荟萃分析声明的首选报告项目(PRISMA),本系统评价纳入了在健康人类受试者中进行的测试中华o.s ensis相对于安慰剂的疗效和有效性的随机研究。检索PubMed、Library of Congress、JISC Library、Clinical Trials.gov、mRCT、谷歌Scholar、Embase、Web of Science、CINAHL、Medline和Cochrane。在4,308篇可能相关的文章中,29篇全文文章被审查,其中7篇是在健康人类受试者中进行的随机试验。所有的研究都被归类为低风险,共有286名参与者。在纳入的研究中,有5项注意到组前/组后的显著差异。5 .研究结果支持了青花草作为一种有效的膳食补充剂的利用。补充中华o.p.对有氧运动表现的影响可能对各种运动项目有影响。在纳入的研究中,不充分报告中华o.s ensis制剂的细节是一个常见的问题。尽管付出了巨大的努力,但仍有可能没有获得所有相关数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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