Effects of maternal folic acid supplementation on renal urinary system development in human offspring—a meta-analysis and systemic review

Minghui Yu, Qian Shen
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Abstract

Background: The effectiveness of maternal folate acid (FA) supplementation during pregnancy in reducing the risk of neural tube defects (NTDs) is already well established. However, the effect of maternal FA supplementation on congenital anomalies of the kidney and urinary tract (CAKUT) has scarcely been investigated. This study aimed to investigate the evidence of associations between maternal FA supplementation and offspring renal urinary system abnormality outcomes.
母体叶酸补充对人类后代肾脏泌尿系统发育的影响——荟萃分析和系统回顾
背景:孕妇在妊娠期间补充叶酸(FA)降低神经管缺陷(NTDs)风险的有效性已经得到了很好的证实。然而,母体补充FA对先天性肾和尿路异常(CAKUT)的影响几乎没有研究。本研究旨在探讨母体补充FA与子代肾脏泌尿系统异常结局之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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