Pattern of Donor Adverse Reactions in Blood Donation in a Tertiary Care Hospital in Bangalore, India

M Beulah, Joseph Latha Fathima
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Abstract

Introduction: Blood is one of the unique and precious gift that one person can give to another person. Most donors tolerate blood donation well, but sometimes donors can develop adverse reactions. Aim: To analyse the pattern of donor adverse reactions in blood donation in a tertiary care hospital in Bangalore, India. Materials and Methods: It was an ambispective cross- sectional study. Donors who developed adverse reactions over a period of three years from January 2018 to December 2020 (January 2018 to December 2019- retrospective and January 2020 to December 2020- prospective) in a tertiary care hospital in Bangalore were studied. The parameters analysed were the type of adverse reaction (systemic and local), the reaction in first-time donors or repeated donors, and the gender of the donor. Stata 2016 version was used in the analysis of data. Adverse Donor Reaction (ADR) is reported as a percentage and 95% confidence interval. The percentage of ADR in males and females was compared using the Chi-square test. Results: The population studied consisted of 37,007 whole blood donors, with 35347 (95.51%) males and 1660 (4.48%) females. Among 37,007 donors, 316 donors 316/37007 (0.85%) had adverse reactions out of which, 287 were males and 29 females. There were 238 first-time donors and 78 repeat donors. The Vasovagal Reaction (VVR) was the most common 307 donors (97.15%) systemic ADR seen. Local reactions were seen in 9 donors (2.84%). Conclusion: The number of donors who developed ADRs was low still it is desirable to reduce risks. The ADRs can be reduced by diligently following the screening protocols and carrying out the venipuncture precisely.
印度班加罗尔一家三级医院献血中献血者不良反应的模式
血液是一种独特而珍贵的礼物,一个人可以送给另一个人。大多数献血者对献血耐受良好,但有时献血者会出现不良反应。目的:分析印度班加罗尔某三级医院献血中献血者不良反应的模式。材料与方法:本研究为双侧面横断面研究。对班加罗尔一家三级医院2018年1月至2020年12月(2018年1月至2019年12月-回顾性,2020年1月至2020年12月-前瞻性)三年内出现不良反应的供体进行了研究。分析的参数包括不良反应类型(全身和局部)、首次或多次献血者的反应以及献血者的性别。数据分析采用Stata 2016版本。供体不良反应(ADR)以百分比和95%置信区间报告。采用卡方检验比较男女不良反应发生率。结果:研究人群包括37007例全血献血者,其中男性35347例(95.51%),女性1660例(4.48%)。37007例献血者中有316例(316/37007,0.85%)出现不良反应,其中男性287例,女性29例。首次献血者238人,重复献血者78人。血管迷走神经反应(VVR)是307例供者中最常见的,占97.15%。局部反应9例(2.84%)。结论:献血者发生不良反应的人数虽少,但仍应降低风险。通过严格遵循筛选方案和精确进行静脉穿刺,可以减少不良反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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