Action of ultra-diluted ethanol extract of Bryonia alba on HepG2 liver cancer cells

Abstract

Objectives In this study we explored Bryonia alba as a new anti-cancer agent against liver cancer cells. Material and Methods The Bryonia 6C - an alternative medicine was applied on HepG2 liver cancer cell line to find out its effectiveness indicating morphological and cytokine changes by observing cytopathic effect and RT-PCR study. Results The result showed a possible anti-cancer effect of Bryonia 6C with degenerative changes on the cancer cells. A cytokine imbalance was also noticed within 24 hours detrimental to the malignant environment of these cells. Conclusion The alternative medicine Bryonia 6C is an effective anticancer agent against liver cancer cells.