An additively manufactured model for preclinical testing of cervical devices

IF 3.4 3区 医学 Q1 ORTHOPEDICS
JOR Spine Pub Date : 2023-10-06 DOI:10.1002/jsp2.1285
Jenna M. Wahbeh, Erika Hookasian, John Lama, Labiba Alam, Sang-Hyun Park, Sophia N. Sangiorgio, Edward Ebramzadeh
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引用次数: 0

Abstract

Purpose

Composite models have become commonplace for the assessment of fixation and stability of total joint replacements; however, there are no comparable models for the cervical spine to evaluate fixation. The goal of this study was to create the framework for a tunable non-homogeneous model of cervical vertebral body by identifying the relationships between strength, in-fill density, and lattice structure and creating a final architectural framework for specific strengths to be applied to the model.

Methods

The range of material properties for cervical spine were identified from literature. Using additive manufacturing software, rectangular prints with three lattice structures, gyroid, triangle, zig-zag, and a range of in-fill densities were 3D-printed. The compressive and shear strengths for all combinations were calculated in the axial and coronal planes. Eleven unique vertebral regions were selected to represent the distribution of density. Each bone density was converted to strength and subsequently correlated to the lattice structure and in-fill density with the desired material properties. Finally, a complete cervical vertebra model was 3D-printed to ensure sufficient print quality.

Results

Materials testing identified a relationship between in-fill densities and strength for all lattice structures. The axial compressive strength of the gyroid specimens ranged from 1.5 MPa at 10% infill to 31.3 MPa at 100% infill and the triangle structure ranged from 2.7 MPa at 10% infill to 58.4 MPa at 100% infill. Based on these results, a cervical vertebra model was created utilizing cervical cancellous strength values and the corresponding in-fill density and lattice structure combination. This model was then printed with 11 different in-fill densities ranging from 33% gyroid to 84% triangle to ensure successful integration of the non-homogeneous in-fill densities and lattice structures.

Conclusions

The findings from this study introduced a framework for using additive manufacturing to create a tunable, customizable biomimetic model of a cervical vertebra.

Abstract Image

用于宫颈装置临床前测试的快速制造模型
目的 复合模型已成为评估全关节置换固定性和稳定性的常用方法,但目前还没有可用于评估颈椎固定性的类似模型。本研究的目的是通过确定强度、填充密度和晶格结构之间的关系,为可调非均质颈椎体模型创建框架,并为应用于模型的特定强度创建最终架构框架。 方法 从文献中确定颈椎的材料属性范围。使用增材制造软件,三维打印出了具有三种晶格结构(陀螺形、三角形、人字形)和一系列填充密度的矩形打印件。计算了所有组合在轴向和冠状面上的抗压和抗剪强度。选择了 11 个独特的脊椎区域来代表密度分布。每个骨密度都被转换为强度,随后与具有所需材料特性的晶格结构和填充密度相关联。最后,对完整的颈椎模型进行 3D 打印,以确保足够的打印质量。 结果 材料测试确定了所有晶格结构的填充密度与强度之间的关系。陀螺试样的轴向抗压强度从 10%填充时的 1.5 兆帕到 100%填充时的 31.3 兆帕不等,三角形结构的轴向抗压强度从 10%填充时的 2.7 兆帕到 100%填充时的 58.4 兆帕不等。根据这些结果,利用颈椎松质骨强度值以及相应的填充密度和晶格结构组合创建了颈椎模型。然后用 11 种不同的填充密度(从 33% 的陀螺状密度到 84% 的三角形密度)对该模型进行打印,以确保非均质填充密度和晶格结构的成功整合。 结论 本研究的结果为使用快速成型技术创建可调整、可定制的颈椎仿生模型提供了一个框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
JOR Spine
JOR Spine ORTHOPEDICS-
CiteScore
6.40
自引率
18.90%
发文量
42
审稿时长
10 weeks
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