Agustin J. Nanda De Niro, Gede Wirya Kusuma Duarsa, I Wayan Yudiana, Nyoman Gede Prayudi, Pande Made Wisnu Tirtayasa, Kadek Budi Santosa, Yudhistira Pradnyan Kloping
{"title":"Predictors of priapism incidence and recurrence in sickle cell disease patients","authors":"Agustin J. Nanda De Niro, Gede Wirya Kusuma Duarsa, I Wayan Yudiana, Nyoman Gede Prayudi, Pande Made Wisnu Tirtayasa, Kadek Budi Santosa, Yudhistira Pradnyan Kloping","doi":"10.1186/s12301-023-00376-0","DOIUrl":null,"url":null,"abstract":"Abstract Background Sickle cell disease (SCD) is a prevalent genetic blood disorder with a high global incidence rate. Individuals with SCD experience lifelong complications; one such recurrent complication is priapism. Given the unfavorable prognosis and the limited knowledge of patients regarding priapism, healthcare professionals need to identify factors that can aid in diagnosing priapism in SCD patients. Main body of the abstract A comprehensive literature search was conducted using four databases, namely MEDLINE, The Cochrane Library, ScienceDirect, and Google Scholar, following the PRISMA guidelines. The quality and risk of bias assessment were performed using the ROBINS-I tool (Risk Of Bias in Non-Randomized Studies of Interventions) according to guidelines by the Cochrane Collaboration. The literature search yielded a total of 4434 studies, out of which six studies met the eligibility criteria. Short conclusions The findings from the selected studies revealed that advancing age and a higher frequency of priapism episodes were significant predictors of priapism occurrence in SCD patients. These findings underscore the importance of early recognition and management of priapism in this patient population.","PeriodicalId":7432,"journal":{"name":"African Journal of Urology","volume":"14 1","pages":"0"},"PeriodicalIF":0.5000,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African Journal of Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s12301-023-00376-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract Background Sickle cell disease (SCD) is a prevalent genetic blood disorder with a high global incidence rate. Individuals with SCD experience lifelong complications; one such recurrent complication is priapism. Given the unfavorable prognosis and the limited knowledge of patients regarding priapism, healthcare professionals need to identify factors that can aid in diagnosing priapism in SCD patients. Main body of the abstract A comprehensive literature search was conducted using four databases, namely MEDLINE, The Cochrane Library, ScienceDirect, and Google Scholar, following the PRISMA guidelines. The quality and risk of bias assessment were performed using the ROBINS-I tool (Risk Of Bias in Non-Randomized Studies of Interventions) according to guidelines by the Cochrane Collaboration. The literature search yielded a total of 4434 studies, out of which six studies met the eligibility criteria. Short conclusions The findings from the selected studies revealed that advancing age and a higher frequency of priapism episodes were significant predictors of priapism occurrence in SCD patients. These findings underscore the importance of early recognition and management of priapism in this patient population.
背景镰状细胞病(SCD)是一种普遍存在的遗传性血液疾病,全球发病率很高。SCD患者会经历终身并发症;其中一个反复出现的并发症是阴茎勃起。考虑到不良的预后和患者对阴茎勃起障碍的有限知识,医疗保健专业人员需要确定有助于诊断SCD患者阴茎勃起障碍的因素。采用MEDLINE、the Cochrane Library、ScienceDirect和Google Scholar四个数据库,按照PRISMA指南进行全面的文献检索。采用ROBINS-I (risk of bias in Non-Randomized Studies of Interventions)工具,按照Cochrane Collaboration的指南进行偏倚质量和风险评估。文献检索共获得4434项研究,其中6项研究符合入选标准。简短的结论:所选研究的结果表明,年龄的增长和较高的阴茎勃起发作频率是SCD患者阴茎勃起的重要预测因素。这些发现强调了在这类患者中早期识别和治疗阴茎勃起障碍的重要性。