EFFECT OF ROBUSTA COFFEE BEANS AND ARABICA EXTRACT GEL AS INFLAMATION PULP MATERIAL

Sherli Diana, Nadiya Amalia, Deby Kania Tri Putri
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Abstract

Background: Reversible pulpitis is a mild to moderate inflammatory pulp condition often treated with pulp capping treatments. Current study states that calcium hydroxide (CaOH2) has drawbacks for a long-time use. One of the alternative pulp capping materials is Robusta and Arabica coffee bean extract gel which contains flavonoid compounds and chlorogenic acid which have immunomodulatory properties that play role in the pulp inflammatory process by increasing the count of lymphocyte. Objective: The goal of this study is to determine and analyse the effect of Robusta coffee bean and Arabica coffee bean extract gel 95% to the of lymphocyte cells count on the 3rd and 5th day of pulp inflammation compared to placebo gel. Materials and Methods: This research is a true experimental with a post-test only control group design. This study used three treatment groups; Robusta coffee bean extract gel 95%, Arabica coffee bean extract gel 95%, and control group placebo gel. Results: Two Way Anova test results obtained p<0.05, showed significant difference. Data analysis was continued with the Post Hoc Bonferroni test which showed that there was a significant difference between the 95% Robusta coffee bean extract gel group and the 95% Arabica coffee bean extract gel group with p<0.05. Conclusion: The administration of Robusta coffee bean extract gel with a concentration of 95% can increase the of lymphocyte cells count in pulp inflammation on the 3rd and 5th days more effectively than the 95% Arabica coffee bean extract gel. Keywords: Arabica Coffee, Direct Pulp Capping, Inflammation, Lymphocytes, Pulpitis, Robusta Coffee
罗布斯塔咖啡豆和阿拉比卡提取物凝胶作为炎症浆材料的效果
背景:可逆性牙髓炎是一种轻至中度的牙髓炎症性疾病,通常采用牙髓盖盖治疗。目前的研究表明,氢氧化钙(CaOH2)长期使用有缺点。其中一种替代的纸浆覆盖材料是罗布斯塔和阿拉比卡咖啡豆提取物凝胶,其中含有黄酮类化合物和绿原酸,它们具有免疫调节特性,通过增加淋巴细胞计数在纸浆炎症过程中发挥作用。目的:本研究的目的是确定和分析罗布斯塔咖啡豆和阿拉比卡咖啡豆提取物凝胶95%与安慰剂凝胶相比,对牙髓炎症第3天和第5天淋巴细胞计数的影响。材料与方法:本研究是一个真正的实验,只有测试后的对照组设计。本研究采用三个治疗组;罗布斯塔咖啡豆提取物凝胶95%,阿拉比卡咖啡豆提取物凝胶95%,对照组安慰剂凝胶。结果:双因素方差分析结果为p<0.05,差异有统计学意义。采用Post Hoc Bonferroni检验继续进行数据分析,95%罗布斯塔咖啡豆提取物凝胶组与95%阿拉比卡咖啡豆提取物凝胶组之间差异显著,p < 0.05。结论:95%浓度的罗布斯塔咖啡豆提取物凝胶比95%阿拉比卡咖啡豆提取物凝胶更能有效地增加第3和第5天牙髓炎症的淋巴细胞计数。关键词:阿拉比卡咖啡,直接盖髓,炎症,淋巴细胞,牙髓炎,罗布斯塔咖啡
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