New frontiers in linguistic research: Eliminating the challenges of understanding the genetics of language through bioinformatics

IF 0.7 3区文学 0 HUMANITIES, MULTIDISCIPLINARY

Digital Scholarship in the Humanities Pub Date : 2023-06-15 DOI:10.1093/llc/fqad040

Annuncy Vinoliya, Joseph Ponniah

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引用次数: 0

Abstract

Abstract The contemporary research in linguistics aims to forge an understanding of consilience by evading the stereotypic semantic studies in linguistics. Modern linguistics calls for understanding language evolution, language production, and language disorders in association with neuro-genetic studies. To undertake genetic trials, language scholars from the humanities and social sciences disciplines have constraints like funding, inaccessibility to genetic labs, and ethical issues over biological bodies. To resolve the constraints and to enhance extensive knowledge on the genetic association with language, this article employs bioinformatics tools, namely the Basic Local Alignment Search Tool (BLAST) and the Sorting Intolerant From Tolerant (SIFT). Through the BLAST tool, the article aids the language researcher to understand language evolution, and through the application of SIFT, the article highlights mutation points in the gene of a severe speech disorder. Finally, the article emphasizes the inclusion of bioinformatics in the field of humanities and social sciences with respect to language studies

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语言学研究的新领域:通过生物信息学消除理解语言遗传学的挑战

当代语言学研究的目的是摆脱语言学中语义学研究的刻板印象，形成对顺应性的理解。现代语言学要求理解与神经遗传研究相关的语言进化、语言产生和语言障碍。为了进行基因试验，来自人文和社会科学学科的语言学者受到资金、无法进入基因实验室和生物身体伦理问题等方面的限制。为了解决这些限制并增强对语言遗传关联的广泛了解，本文采用了生物信息学工具，即基本局部比对搜索工具(BLAST)和不耐受从耐受排序工具(SIFT)。本文通过BLAST工具帮助语言研究者了解语言的进化，通过SIFT的应用，突出了一个严重语言障碍基因的突变点。最后，文章强调了将生物信息学纳入语言研究的人文社会科学领域

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来源期刊

Digital Scholarship in the Humanities Multiple-

CiteScore

1.80

自引率

25.00%

发文量

期刊介绍： DSH or Digital Scholarship in the Humanities is an international, peer reviewed journal which publishes original contributions on all aspects of digital scholarship in the Humanities including, but not limited to, the field of what is currently called the Digital Humanities. Long and short papers report on theoretical, methodological, experimental, and applied research and include results of research projects, descriptions and evaluations of tools, techniques, and methodologies, and reports on work in progress. DSH also publishes reviews of books and resources. Digital Scholarship in the Humanities was previously known as Literary and Linguistic Computing.