Effect of Previous Stent Implantation in Elective Coronary Artery Bypass Grafting Operation; Multivariate Analysis of 1,259 Patients: Retrospective Clinical Trial

Mehmet Erdem TOKER, Muharrem DAĞLI, Cüneyt ARKAN, Ömer Faruk AKARDERE
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Abstract

Objective: This study aims to investigate the effect of previous stent implantation on early mortality in patients undergoing elective coronary artery bypass grafting (CABG). Material and Methods: A total of 1,259 patients who underwent elective isolated CABG between January 2015 and December 2016 were included. There were 970 patients in the CABG without stent group and 289 patients in the CABG with stent group. Preoperative, intraoperative, and postoperative data of both groups were compared. Predictors of early mortality in CABG were examined using the logistic regression analysis. Results: Early mortality rates after surgery between the groups were similar (CABG without stent group vs. CABG with stent group; 2.9% vs. 3.1%, p=0.998). The length of intensive care unit stay, the use of intraaortic balloon pump, tracheotomy, new dialysis, revision and the use of extracorporeal membrane oxygenator were also comparable between the groups (p>0.05). The mean number of grafts was significantly lower in the CABG with stent group than the CABG without stent group (2.62±0.91 vs. 2.87±0.9; p<0.001 respectively). Multivariate analysis revealed that an ejection fraction of ≤40% [odds ratio (OR): 3.8; 95% confidence interval (CI): 1.9-7.7; p<0.001], preoperative renal failure (OR: 3.7; 95% CI: 1.5-8.8; p=0.003), and advanced age (OR: 1.07; 95% CI: 1.03-1.1; p<0.001) were independent predictors of early mortality. Previous stent implantation has not been found out as a risk factor for early mortality (OR: 1.08; 95% CI: 0.5-2.3; p=0.998). Conclusion: Previous stent implantation was not found to be a factor affecting early mortality in patients undergoing elective CABG operations.
择期冠状动脉旁路移植术中既往支架植入的影响1259例患者的多因素分析:回顾性临床试验
目的:探讨术前支架植入对择期冠状动脉旁路移植术(CABG)患者早期死亡率的影响。材料和方法:2015年1月至2016年12月期间接受选择性孤立CABG的患者共1259例。无支架搭桥组970例,支架搭桥组289例。比较两组术前、术中、术后资料。采用logistic回归分析对CABG早期死亡的预测因素进行检验。结果:两组术后早期死亡率相似(无支架搭桥组与支架搭桥组;2.9% vs. 3.1%, p=0.998)。重症监护时间、主动脉内气囊泵使用情况、气管切开术、新透析、翻修及体外膜氧合器使用情况两组间也具有可比性(p>0.05)。有支架搭桥组的平均移植物数量明显低于无支架搭桥组(2.62±0.91 vs 2.87±0.9;p < 0.001)。多因素分析显示,射血分数≤40%[比值比(OR): 3.8;95%置信区间(CI): 1.9 ~ 7.7;p<0.001],术前肾功能衰竭(OR: 3.7;95% ci: 1.5-8.8;p=0.003),高龄(OR: 1.07;95% ci: 1.03-1.1;P <0.001)是早期死亡的独立预测因子。既往支架植入未被发现是早期死亡的危险因素(OR: 1.08;95% ci: 0.5-2.3;p = 0.998)。结论:既往支架植入未发现是影响择期冠脉搭桥患者早期死亡的因素。
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