Evaluating Transcranial Direct Current Stimulation as an Adjunct to Inpatient Physiotherapy in Paediatric Acquired Brain Injury: A Randomized Feasibility Trial

IF 0.9 4区医学 Q4 REHABILITATION

Physiotherapy Canada Pub Date : 2023-09-26 DOI:10.3138/ptc-2023-0015

Jennifer L. Ryan, Deryk S. Beal, Darcy L. Fehlings, Danielle E. Levac, Anna Tendera, F. Virginia Wright

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引用次数: 1

Abstract

Purpose: Evaluate the feasibility of transcranial direct current stimulation (tDCS) as an adjunct to inpatient physiotherapy for children and youth with acquired brain injury (ABI). Method: This randomized feasibility trial allocated children (5–18 years of age with moderate to severe ABI) to receive either active or sham anodal tDCS immediately prior to 16 of their existing inpatient physiotherapy sessions. Participants, physiotherapists, assessors, and primary investigators were blinded to treatment allocation. Eligibility, recruitment, retention, tolerance, and preliminary treatment outcomes were evaluated against a priori feasibility targets. Results: Of 232 children admitted over 21 months, six were eligible (2.6%) and four were recruited (66.7%). One participant completed the entire study protocol, two were withdrawn for unrelated changes in medical stability, and one could not commence the study due to COVID-19 restrictions. Participants completed all tDCS sessions that were started with the primary transient side effect being sub-electrode itchiness. Conclusions: While the study was infeasible from eligibility and retention perspectives, study procedures (e.g., assessment, treatment, side effect tracking, physiotherapy documentation) were viable and should be applied to future paediatric tDCS studies.

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评估经颅直流电刺激作为儿科获得性脑损伤住院物理治疗的辅助:一项随机可行性试验

目的:评价经颅直流电刺激(tDCS)作为儿童和青少年获得性脑损伤(ABI)住院物理治疗辅助治疗的可行性。方法:这项随机可行性试验分配儿童(5-18岁，中度至重度ABI)，在他们现有的16次住院物理治疗之前立即接受主动或假无节点tDCS。参与者、物理治疗师、评估员和主要调查人员对治疗分配不知情。资格、招募、保留、耐受性和初步治疗结果根据先验可行性目标进行评估。结果:在232名21个月以上的儿童中，6名(2.6%)符合条件，4名(66.7%)被招募。一名参与者完成了整个研究方案，两名参与者因不相关的医疗稳定性变化而被撤回，一名参与者因COVID-19限制而无法开始研究。参与者完成了所有的tDCS疗程，开始时主要的短暂副作用是亚电极瘙痒。结论:虽然从资格和保留角度来看，该研究不可行，但研究程序(如评估、治疗、副作用跟踪、物理治疗记录)是可行的，应该应用于未来的儿科tDCS研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Physiotherapy Canada REHABILITATION-

CiteScore

1.90

自引率

20.00%

发文量

审稿时长

>12 weeks

期刊介绍： Physiotherapy Canada is the official, scholarly, refereed journal of the Canadian Physiotherapy Association (CPA), giving direction to excellence in clinical science and reasoning, knowledge translation, therapeutic skills and patient-centred care. Founded in 1923, Physiotherapy Canada meets the diverse needs of national and international readers and serves as a key repository of inquiries, evidence and advances in the practice of physiotherapy. Physiotherapy Canada publishes the results of qualitative and quantitative research including systematic reviews, meta analyses, meta syntheses, public/health policy research, clinical practice guidelines, and case reports. Key messages, clinical commentaries, brief reports and book reviews support knowledge translation to clinical practice. In addition to delivering authoritative, original scientific articles and reports of significant clinical studies, Physiotherapy Canada’s editorials and abstracts are presented in both English and French, expanding the journal’s reach nationally and internationally. Key messages form an integral part of each research article, providing a succinct summary for readers of all levels. This approach also allows readers to quickly get a feel for ‘what is already known’ and ‘what this study adds to’ the subject. Clinician’s commentaries for key articles assist in bridging research and practice by discussing the article’s impact at the clinical level. The journal also features special themed series which bring readers up to date research supporting evidence-informed practice. The Canadian Physiotherapy Association (CPA) is the national professional association representing almost 15,000 members distributed throughout all provinces and territories. CPA’s mission is to provide leadership and direction to the physiotherapy profession, foster excellence in practice, education and research, and promote high standards of health in Canada.