Lipid biosynthesis in Paramphistomum microbothrium (Trematoda).

Abstract

In vitro studies with Paramphistomum microbothrium indicated that the trematode is capable of synthesizing its complex lipids using exogenous substrates. U-14C glucose and 2-14C acetate were predominantly incorporated into phospholipids while 1-14C oleic acid and U-14C palmitic acid appeared more in the neutral lipids. A large proportion of the labelled acetic acid incorporated into neutral lipids appeared in the triglycerides. P. microbothrium is capable of synthesizing its cholesterol de novo.