Do atmospheric pollution and fine particulate matter aggravate COVID-19?

F. Marano, F. Squinazi
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Abstract

On observing a coincidence between larger COVID-19 clusters and atmospheric pollution in the first pandemic wave, in Wuhan, China, then in Northern Italy, researchers began to associate severe cases with elevated levels of atmospheric pollutants in heavily populated industrial regions. Fine and ultra fine particles in particular were suspected of carrying and spreading the virus and aggravating the disease. Data acquired in recent months show that chronic PM and NO2 pollution, rather than their peaks, are associated with case numbers and severe forms of the disease. There are two possible explanations: an increase in pulmonary inflammation among individuals already weakened by an overexpression of the ACE2 receptor under the effect of chronic pollution, and the idea that atmospheric particles transport SARS-CoV-2, which has not yet been demonstrated.
大气污染和细颗粒物会加重COVID-19吗?
研究人员观察到,在中国武汉和意大利北部的第一波大流行中,更大的COVID-19聚集群与大气污染之间存在巧合,他们开始将严重病例与人口稠密的工业区大气污染物水平升高联系起来。特别是细颗粒和超细颗粒被怀疑携带和传播病毒并加重疾病。近几个月获得的数据表明,慢性PM和NO2污染与病例数和疾病的严重形式有关,而不是它们的峰值。有两种可能的解释:在慢性污染的影响下,由于ACE2受体的过度表达,已经减弱的个体的肺部炎症增加,以及大气颗粒运输SARS-CoV-2的想法,这尚未得到证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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