Neural instability and delicacy while the electro-encephalography indicator of epileptic seizure (e-seizure) on set zone

V. R. Raju
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引用次数: 0

Abstract

More than 15 million seizure-epileptic subjects (patients) do not respond to medication globally. Surgery necessitates thorough elimination or separation of the epileptic-seizure onset zone (ESoZ), regions of epileptic brains where seizures derive (come from). Sadly, the success rates of operation differ amongst 32% and 72% and this is due to clinically and hence prognostically no authenticated or substantiated (i.e., corroborated) biological or physiological indicator of the ESoZ exists. We discuss, as well as confirm a new electro encephalography indication neural vulnerability in a retroactive study of 90 subjects (patients) by applying neural instability of the interpreted ESoZ as a metrical to expect operational (invasive) results in retrospect (retrospectively). Susceptibility expects (43/47) surgical (invasive)-failures, as well as a total likelihood precision of 76% assessed through the precision of neuroscientists at 48% (positive-results).
神经不稳定和敏感,而癫痫发作的脑电图指标(e-癫痫)在设定区域
全球有超过1500万癫痫患者(患者)对药物无反应。手术需要彻底消除或分离癫痫发作区(ESoZ),即癫痫发作源自的癫痫大脑区域。遗憾的是,手术成功率在32%和72%之间存在差异,这是由于临床上和预后上没有经过验证或证实的(即确证的)ESoZ的生物或生理指标存在。我们在一项对90名受试者(患者)的回顾性研究中讨论并证实了一种新的脑电图指示神经易损性,通过将解释的ESoZ的神经不稳定性作为一种测量方法来预测手术(侵入性)结果(回顾性)。易感性预期手术(侵入性)失败(43/47),以及总似然精度为76%,通过神经科学家的精度评估为48%(阳性结果)。
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