[Studies on the production of epidermal cytokines after UVB irradiation in patients with epidermodysplasia verruciformis].

IF 0.5 Q4 DERMATOLOGY
Przeglad dermatologiczny Pub Date : 1990-11-01
S Majewski, J Malejczyk, A Urbanski, T Schwarz, M Malejczyk, J Misiewicz, L Rudnicka, J Szymańczyk, T A Luger, S Jabłońska
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引用次数: 0

Abstract

The production of interleukin-1 (IL-1) and interleukin-1 inhibitor by keratinocytes isolated from the skin of epidermodysplasia verruciformis patients was studied. Keratinocytes from uninvolved skin of patients with most pronounced neoplastic lesions produced large amounts of an IL-1 inhibitor (20-40 kD). Keratinocytes from preneoplastic lesions showed no significant differences compared to cells from healthy donors but their production of IL-1 after UVB irradiation was increased.

[UVB照射后疣状表皮发育不良患者表皮细胞因子产生的研究]。
研究了疣状表皮发育不良患者皮肤角质形成细胞产生白细胞介素-1 (IL-1)和白细胞介素-1抑制剂的情况。来自最明显肿瘤病变患者未受累皮肤的角化细胞产生大量IL-1抑制剂(20-40 kD)。来自肿瘤前病变的角质形成细胞与来自健康供体的细胞相比没有显著差异,但UVB照射后其IL-1的产生增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
自引率
14.30%
发文量
9
审稿时长
12 weeks
期刊介绍: Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.
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