Current Evidence On The Use Of Curcumin In Modern Periodontology- A Narrative Review

Abstract

Curcumin, the main bioactive ingredient in turmeric, has been used to treat multiple diseases and conditions due to its numerous health benefits and therapeutic effects. The properties of natural and chemically modified curcumin (CMC) have been extensively investigated, with strong evidence on its anti-inflammatory, anti-microbial (antibacterial, antiviral, antifungal properties), antioxidant, anti-angiogenic, anti-carcinogenic, antispasmodic, hepato-protective, and wound healing properties. The aim of this review aims to present an overview of the use of curcumin in periodontal therapy and the biological mechanisms behind its properties. Findings from in vitro studies suggest that curcumin can promote osteogenesis, down regulate proteases, promote wound healing, and suppress periodontal bacteria. Results from animal studies suggest the potential of curcumin to reduce periodontal inflammation and alveolar bone loss. Topical