Stent Design for Compensating Wall Shear Stress via Computational Modeling and Fluid Dynamics

Chun-Ming Chang, Wei Shin Wong, J. Tsai
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Abstract

Stents are meshed tubes used to treat narrowed or weakened arteries. It is observed that the geometrical change created by a deployed stent may influence regional characteristics and blood flow. Restenosis can occur after the stent deployment due to neointimal proliferation. In this paper a new stent design based on a regular stent was proposed to modify the wall shear stress (WSS) of existing stent design. The fluid flow inside the stent region was then compensated to approach a regular level without disturbance of a stent. Simulation results indicated the possibility to reduce the restenosis of current stent designs.
基于计算建模和流体动力学的支架补偿壁剪应力设计
支架是用于治疗狭窄或衰弱动脉的网状管。观察到,部署支架所产生的几何变化可能影响区域特征和血流。由于内膜增生,支架置入后可发生再狭窄。本文在常规支架的基础上提出了一种新型支架设计,以修正现有支架设计中的壁面剪切应力。然后对支架区域内的流体流动进行补偿,使其接近规则水平而不受支架的干扰。仿真结果表明,现有支架设计有可能减少再狭窄。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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