Skin Preparation in Prevention of Surgical Site Infection in Paediatric Abdominal Surgeries at The University of Port Harcourt Teaching Hospital, Nigeria.

Abhulimen Victor, Nwiwu Princewill, I. Gbobo
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Abstract

Purpose: Many studies on preoperative antiseptic agents are inconclusive. This study attempts to find the more effective combination antiseptic agent in pediatric surgical patients. Methodology: This was a prospective randomized study on paediatric patients. Preoperative skin preparation for each group was done with the assigned antiseptic combination. Patients were followed up on the 14th,21st and 30th postoperative days. The primary outcome measures were the incidence of SSI in both groups, Secondary outcome measures was the prevalent flora in patients with SSI. The data from the folders were collected and collated. A ninety-five percent confidence interval and a p-value less than 0.05 was considered significant. Continuous variables were presented in means and standard deviation. Results were presented in tables. Findings: The rate of SSI in the chlorhexidine–alcohol group was 6.9% and that of the povidone–iodine/alcohol group was 9.7%. The odds ratio was 0.71 in favour of the chlorhexidine/alcohol group, but the result was not statistically significant(p=0.228) Organisms isolated were mostly monomicrobial, with Escherichia coli accounting for 50% of the cases. Unique Contributions to Theory, Policy and Practice: The study found that the patients who received chlorhexidine–alcohol as a skin antiseptic had a lower incidence of SSI than those who received povidone-iodine/alcohol; however, this was not statistically significant. Earlier studies had initially stated that the povidone-iodine/alcohol was better.
尼日利亚哈科特港大学教学医院的皮肤准备预防儿科腹部手术手术部位感染。
目的:许多关于术前使用防腐剂的研究尚无定论。本研究旨在为小儿外科患者寻找更有效的联合抗菌剂。方法:这是一项针对儿科患者的前瞻性随机研究。各组术前皮肤准备使用指定的抗菌组合。分别于术后第14、21、30天随访。主要指标是两组患者的SSI发生率,次要指标是SSI患者的流行菌群。从文件夹中收集并整理了数据。95%的置信区间和p值小于0.05被认为是显著的。连续变量以均值和标准差表示。结果以表格形式呈现。结果:氯己定-酒精组SSI发生率为6.9%,聚维酮-碘/酒精组为9.7%。氯己定/酒精组优势比为0.71,但差异无统计学意义(p=0.228)。分离的微生物以单菌为主,大肠杆菌占50%。对理论、政策和实践的独特贡献:研究发现,使用氯己定-酒精作为皮肤防腐剂的患者的SSI发生率低于使用聚维酮-碘/酒精的患者;然而,这在统计学上并不显著。早期的研究最初表明,聚维酮碘/酒精更好。
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