Health-related quality of life and its predicting factors among male oral cancer survivors in Sri Lanka: A cross sectional study

Madara Fernando, Maheshika Weththasinghe, D. Wanigasekara, Anjalee Chandrathilaka, Samith Dissanayaka, Deshitha Withana, Nimantha Karunathilaka, T. Amarasekara
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Abstract

Introduction: Health-related quality of life (QoL) and its predicting factors for oral cancer survivors are varied and little evidence is available in Sri Lanka. This descriptive cross-sectional study aimed to assess the QoL and its predicting factors of male oral cancer survivors.Methods: The study was conducted at Apeksha Hospital (National Cancer Institute, Sri Lanka) from June to December 2018 for a period of six months. QoL of 295 oral cancer survivors was assessed using the WHOQoL-BREF questionnaire. The range of QoL score is from 0 to 100 and higher the score, higher the level of QoL Socio-demographic and disease-specific characteristics were considered as predicting factors for QoL and Multiple linear regression was performed to determine the predicting factors. The significant level was kept as p<0.05.Results: The mean score of QoL was averaged among all domains of WHOQoL-BREF questionnaire, which was depicted as 51.9±15, 52.3±19, 49.5±22 and 59.2±16 in Physical, Psychological, Social Relationship and Environment domains respectively. The number of years from diagnosis, metastasis, cancer stage and cancer site were the predictors of the physical health domain while employment status, metastasis, cancer stage and duration of betel chewing for the psychological domain (p<0.05). Age, education status, monthly income, metastasis, and duration of alcohol consumption were identified as the significant predictors of social relationships while employment, monthly income, metastasis, and duration of betel chewing were predictors of the environment domain (p<0.05).Conclusions: The study revealed that QoL of all domains were around average, but each QoL domain has different predicting factors. Therefore, consideration of these predicting factors are immensely helpful to enhance the QoL of these survivors.
斯里兰卡男性口腔癌幸存者的健康相关生活质量及其预测因素:一项横断面研究
口腔癌幸存者的健康相关生活质量(QoL)及其预测因素各不相同,在斯里兰卡几乎没有证据。本研究旨在探讨男性口腔癌幸存者的生活质量及其预测因素。方法:该研究于2018年6月至12月在Apeksha医院(斯里兰卡国家癌症研究所)进行,为期6个月。采用WHOQoL-BREF问卷对295例口腔癌幸存者的生活质量进行评估。生活质量评分范围为0 ~ 100分,评分越高,生活质量水平越高。社会人口学特征和疾病特异性特征作为生活质量的预测因素,采用多元线性回归确定预测因素。以p<0.05保持显著水平。结果:WHOQoL-BREF问卷各领域的生活质量平均得分分别为51.9±15分、52.3±19分、49.5±22分和59.2±16分。诊断年限、肿瘤转移、肿瘤分期和肿瘤部位是生理健康领域的预测因子,就业状况、肿瘤转移、肿瘤分期和咀嚼槟榔时间是心理健康领域的预测因子(p<0.05)。年龄、受教育程度、月收入、转移和饮酒持续时间是社会关系的显著预测因素,而就业、月收入、转移和咀嚼槟榔持续时间是环境领域的显著预测因素(p<0.05)。结论:各领域的生活质量均接近平均水平,但各领域存在不同的预测因素。因此,考虑这些预测因素对提高这些幸存者的生活质量有很大的帮助。
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