Selection criteria for patients with hepatocellular carcinoma for liver transplantation

Abstract

The paper considers the selection criteria for liver transplantation for patients with hepatocellular carcinoma (HCC). Liver resection is an effective method of radical treatment in the early stages of HCC. However, severe liver cirrhosis precludes this method of therapy. For these patients, liver transplantation is a good alternative. The article discusses the problem of correct selection of patients for liver transplantation. Best practices in assessing various criteria for liver transplantation are described. Statistical data are provided. There are also examples of studies that analyze additional factors used as extended criteria for liver transplantation: AFP, PIVKA, the effectiveness of locoregional therapy. The article focuses on neoadjuvant therapy, presents the results of global research on neoadjuvant therapy, and emphasizes their importance.