[Local use of leukotriene inhibitor--NDGA in psoriasis].

IF 0.5 Q4 DERMATOLOGY

Przeglad dermatologiczny Pub Date : 1990-07-01

A Szmurło

引用次数: 0

Abstract

NDGA is known as an inhibitor of leukotrienes and may exert some effect on psoriatic lesion formation. The aim of the study was to test the influence of this drug on appearance of psoriatic plaques. 7 day application of 0.015% NDGA on psoriatic lesions under occlusion in 23 patients, gave some flattening of lesions as compared to controls. However, after finishing of application all the changes reappeared in previous form. We have never observed permanent beneficial effect in any patient.

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白三烯抑制剂NDGA在银屑病中的局部应用

NDGA被认为是白三烯的抑制剂，可能对银屑病病变的形成有一定的影响。这项研究的目的是测试这种药物对银屑病斑块外观的影响。应用0.015% NDGA治疗23例银屑病病变7天，与对照组相比，病变变平。然而，在完成申请后，所有的更改都以以前的形式重新出现。我们从未在任何患者身上观察到永久性的有益效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Przeglad dermatologiczny DERMATOLOGY-

CiteScore

0.80

自引率

14.30%

发文量

审稿时长

12 weeks

期刊介绍： Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.