[Generalized pustular psoriasis in siblings].

S Ohyanagi, M Kanamori, Y Taniguchi, M Shimizu
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Abstract

Generalized pustular psoriasis in siblings, 31-year-old male and 26-year-old female, is presented. In both cases, pustular lesions appeared in childhood and typical eruption of psoriasis vulgaris was not observed during their clinical course. Cholecystitis and chronic tonsillitis of the brother and periodontitis and chronic tonsillitis of the sister were considered to be possible provocative factors. HLA-A24, Bw52-, DR2, as the common HLA haplotype in our cases, was estimated.

兄弟姐妹的广泛性脓疱性银屑病。
兄弟姐妹,31岁男性和26岁女性,普遍化脓疱性牛皮癣。在这两个病例中,脓疱病变出现在儿童时期,在临床过程中没有观察到典型的寻常型银屑病的爆发。兄弟的胆囊炎和慢性扁桃体炎以及妹妹的牙周炎和慢性扁桃体炎被认为是可能的诱发因素。HLA- a24, Bw52-, DR2是我们病例中常见的HLA单倍型。
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