Análisis descriptivo de adultos mayores mexicanos con enfermedad COVID-19

Carla Paola Sánchez-Ríos, J. O. Barreto-Rodríguez, Gustavo Iván Centeno-Sáenz, Hazel Vázquez-Rojas
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Abstract

. Introduction: The elderly may represent a specific group of patients at high risk for developing COVID-19 with rapidly progressive clinical deterioration. In fact, in older individuals, immunosenescence and comorbid disorders are more likely to promote a virus-induced cytokine storm resulting in life-threatening respiratory failure and multi- system compromise. Material and methods: A descriptive study of the geriatric population with COVID-19 disease attended at the National Institute of Respiratory Diseases, Mexico City, Mexico in the period March-May 2020 was carried out. 35 hospitalized adult patients over 60 years were confirmed by RT PCR. for COVID-19 disease in pharyngeal exudate. Descriptive statistics were used and results were expressed using measures of central tendency. Results: A total sample of 35 patients was analyzed. 62.85% were male (n = 22). Systemic arterial hypertension was documented in 51.42% (n = 18), obesity in 48.57% (n = 17) and diabetes mellitus in 34.28% (n = 12). The severity of the COVID-19 disease at the time of hospital admission was: mild in 22.85% (n = 8), moderate in 42.85% (n = 15) and severe or critical in 34.28% (n = 12). 80% (n = 28) consulted after presenting symptoms for more than five days. The tomographic findings were ground glass pattern in 82.85% (n = 29), consolidation in 14.28% (n = 5) and «crazy paving» in only one patient (2.8%). The mortality registered in geriatric patients with COVID-19 was 68.57%. Conclusions: The geriatric population is considered vulnerable for the development of COVID-19 disease and for fatal outcomes. Patients with moderate disease should be closely monitored as they tend to eventually develop critical forms. The fatality of COVID-19 disease in older adult patients is high.
墨西哥老年COVID-19患者的描述性分析
. 老年人可能是新冠肺炎的高危患者群体,其临床进展迅速。事实上,在老年人中,免疫衰老和合并症更有可能促进病毒诱导的细胞因子风暴,导致危及生命的呼吸衰竭和多系统损害。材料和方法:对2020年3月至5月期间在墨西哥墨西哥城国家呼吸疾病研究所参加的COVID-19疾病老年人群进行了描述性研究。采用RT - PCR方法对35例60岁以上住院成人患者进行确诊。咽渗出物中COVID-19疾病使用描述性统计,并使用集中趋势度量来表示结果。结果:共分析35例患者。男性占62.85% (n = 22)。系统性动脉高血压患者占51.42% (n = 18),肥胖患者占48.57% (n = 17),糖尿病患者占34.28% (n = 12)。入院时新冠肺炎严重程度为:轻度占22.85% (n = 8),中度占42.85% (n = 15),重度或危重症占34.28% (n = 12)。80% (n = 28)在出现症状5天以上后就诊。断层扫描表现为磨玻璃纹29例(82.85%),实变5例(14.28%),“疯狂铺路”1例(2.8%)。老年患者新冠肺炎病死率为68.57%。结论:老年人群被认为是COVID-19疾病发展和致命结局的易感人群。中度疾病患者应密切监测,因为他们最终倾向于发展为危重形式。老年成人患者的COVID-19病死率很高。
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