[Determinants of perinatal and infant mortality in Italy 1980-1983].

F Parazzini, N Pirotta, C La Vecchia, L Fedele
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Abstract

Determinants of stillbirth, perinatal and infant mortality in Italy have been analyzed using information collected routinely by the Italian Central Institute of Statistics on more than 2,400,000 births and 33,000 infant deaths in the period 1980-1983. Individual records include data on maternal (for example age, education, obstetric history) and fetal (sex, birth weight, gestational week at birth) characteristics. The Italian stillbirth, perinatal and infant (1st-365th day of life) mortality rates were respectively 7.7/1000 births, 16.4/1000 births and 13.5/1000 livebirths for the considered period. Perinatal and infant mortality was impressive in very low birth weight. About 90% of livebirths weighing less than 1000g died within the first year of life, but this percentage decreased to about 45% in babies weighing 1000-1499g. As a whole, low birth weight explained more than 70% of deaths. Further, stillbirth, perinatal and infant mortality rates were higher in male babies, in older women and in higher birth rank. These findings persist, although less markedly, after adjustment for weight. Mortality rates were about 60-70% higher in less educated women. Stillbirth, perinatal and infant mortality rates were 20 to 30% higher in Southern Italy, as compared to the North of the country. This finding was not markedly changed after adjustment for birth weight and maternal age and education, suggesting that socio-economic factors are per se important determinants of perinatal and infant mortality in Italy, and explain in terms of population attributable risk, about 15% of stillbirths or deaths within the first year of life.

[意大利1980-1983年围产期和婴儿死亡率的决定因素]。
意大利中央统计研究所利用1980-1983年期间收集的关于240多万例出生和33 000例婴儿死亡的信息,对意大利死产、围产期和婴儿死亡率的决定因素进行了分析。个人记录包括产妇(例如年龄、教育程度、产科史)和胎儿(性别、出生体重、出生时妊娠周)特征的数据。在此期间,意大利的死产、围产期和婴儿(出生后第1 -365天)死亡率分别为7.7/1000例、16.4/1000例和13.5/1000例活产。在出生体重非常低的情况下,围产期和婴儿死亡率令人印象深刻。体重低于1000克的活产婴儿中,约90%在出生后一年内死亡,但在体重为1000-1499克的婴儿中,这一比例降至45%左右。总体而言,低出生体重解释了70%以上的死亡。此外,死产、围产期和婴儿死亡率在男婴、年龄较大的妇女和出生等级较高的妇女中较高。在调整体重后,这些发现仍然存在,尽管不那么明显。受教育程度较低的妇女的死亡率高出约60-70%。与意大利北部相比,意大利南部的死产、围产期和婴儿死亡率高出20%至30%。在调整出生体重、产妇年龄和受教育程度后,这一发现没有明显改变,这表明社会经济因素本身是意大利围产期和婴儿死亡率的重要决定因素,并根据人口归因风险解释了大约15%的死产或出生后第一年死亡。
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