Conjugated Linoleic Acid Oils

R. Kapoor, M. Reaney, N. Westcott
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引用次数: 1

Abstract

Conjugated linoleic acid (CLA) is a name given to a mixture of geometric and positional isomers of linoleic acid having conjugated double bonds. Depending on the position and cis-trans-configuration of conjugated double bonds, 54 isomers are possible, of which 14 isomers have been identified in commercial products. CLA was first produced in 1935 via alkali treatment of polyunsaturated fatty acid rich oils. The early research used CLA mainly as a marker for the study of fat metabolism because of its high UV absorbency compared with nonconjugated fat. From the 1980’s, the research interest has increased in its biological properties, particularly its role in cancer, diabetes, and fat metabolism regulation. The present chapter discusses the metabolism, uses, method of production, and analysis of CLA. Keywords: conjugated linoleic acid; CLA; production; analysis; cancer; fat; body composition; diabetes; isomers
共轭亚油酸油
共轭亚油酸(CLA)是具有共轭双键的亚油酸的几何和位置异构体的混合物。根据共轭双键的位置和顺反构型的不同,可能有54种异构体,其中14种已在商业产品中被鉴定。CLA最早是在1935年通过碱法处理富含多不饱和脂肪酸的油脂生产出来的。早期的研究主要将CLA作为脂肪代谢的标志物,因为与非共轭脂肪相比,CLA具有较高的紫外线吸收能力。从20世纪80年代开始,对其生物学特性的研究兴趣有所增加,特别是它在癌症、糖尿病和脂肪代谢调节中的作用。本章讨论了CLA的代谢、用途、生产方法和分析。关键词:共轭亚油酸;班;生产;分析;癌症;脂肪;身体成分;糖尿病;同分异构体
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