Effect of pinealectomy on mitotic activity of adrenal cortex in rats subjected to unilateral adrenalectomy.

Abstract

The effect of pinealectomy on the adrenal growth in unilaterally adrenalectomized rats was studied by evaluation of the mitotic activity of adrenocortical cells on the fifth and tenth day after operation. It was found that pinealectomy resulted in an about double increase of mitotic index on the 5th day after unilateral adrenalectomy, and on the 10th day the stimulatory effect of pinealectomy became less significant.