CMOS Meets Bio

Abstract

There are burgeoning efforts to use CMOS ICs for biotechnology. This paper reviews one such effort, development of a CMOS/Microfluidic hybrid system for magnetic manipulation of biological cells originally reported by the authors in H. Lee et al. (2005, 2006). Programmable magnetic field patterns produced by a CMOS microcoil array IC efficiently manipulate individual cells (tagged by magnetic beads) inside a microfluidic system fabricated on top of the IC.