[Computer-assisted analysis of the pressure behavior of the esophagogastric junction during increase in intragastric pressure].

D Attig, J Petermann, H Klöckner, K D Rosenbaum
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引用次数: 0

Abstract

Two factors are to determine increasing lower esophageal sphincter pressure during intragastric pressure rising mainly: 1. the active intrinsic muscle tone and 2. the efficiency of the law by La Place. The purpose of the study was to estimate the part of both of them in this measurable phenomenon. We investigated 15 healthy volunteers and 5 patients post Nissen fundoplication. A simultaneous manometric examination of gaster and LES was carried out during gradual compression of abdominal wall. Analysis of dependence of LES-pressure on intragastric pressure, based on computer usage, was established. A linear equation described this dependence with the best correlation coefficient (r = 0.98) followed by potential and exponential equation. Fundoplication caused a steeper ascent without any changing of linear character of function. Considering linear equation is compatible with the law by La Place out not with a simultaneous pressure depending change of intrinsic muscle tone, these results indicate that the law by La Place has major importance in the measurable rising of high pressure zone during intragastric pressure increasing.

[计算机辅助分析食管胃交界在胃内压力升高时的压力行为]。
在胃内压升高过程中,决定食管下括约肌压力升高的因素主要有两个:活跃的内在肌张力和2。法律的有效性。这项研究的目的是估计这两种因素在这种可测量现象中的作用。我们调查了15名健康志愿者和5名尼森手术后的患者。在逐渐压迫腹壁的过程中,同时进行胃和LES的压力检查。在计算机应用的基础上,建立了LES-pressure对胃内压的依赖性分析。线性方程描述了最佳相关系数(r = 0.98),其次是势方程和指数方程。复盖引起陡坡上升,但没有改变函数的线性特征。考虑到线性方程与La Place定律相容,但与肌内张力随压力变化的变化不同步,这些结果表明La Place定律对胃内压力升高过程中可测量的高压区升高具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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