[Prolongation of transplantation survival time by a PUVA treatment. Experimental and clinical results].

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR Pub Date : 1990-01-01

S Gruner, H Oesterwitz, J Kaden, H Meffert

引用次数: 0

Abstract

The treatment of transplants by a combination of 8-methoxypsoralen and longwave ultraviolet radiation (PUVA) leads to prolongation of the transplants in allogeneic receivers without immunosuppression. The rejection of skin grafts in the mice could be delayed significantly. The rejection of kidney and heart allografts could be prevented completely. A significant diminution of the acute rejection crises and a raising of the one-year survival rate showed a first clinical study by means of PUVA treatment in human kidney grafts.

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PUVA治疗对移植存活时间的延长。实验及临床结果]。

8-甲氧基补骨脂素联合长波紫外线(PUVA)治疗移植可延长同种异体受体的移植时间，且无免疫抑制。小鼠皮肤移植排斥反应明显延迟。肾脏和心脏异体移植的排斥反应是完全可以预防的。急性排斥反应的显著减少和一年生存率的提高显示了PUVA治疗人类肾移植的首次临床研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR

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