Saudi Consensus Recommendations on the Management of Multiple Sclerosis: Disease-Modifying Therapies and Management of Relapses

Y. Al Malik, Ibtisam A. Al Thubaiti, M. Alammari, Norah Al Fugham, Eman N. Ali, D. Alissa, Salman Aljarallah, A. Al-jedai, Maeed A. AlKathiri, M. AlKhawajah, Mousa A. Almejally, H. Al-Mudaiheem, Hessa S. Al Otaibi, G. Altowaijri, Rumaiza H. Al Yafeai, Mohammed A. Babakkor, S. Bohlega, R. Bunyan, E. Cupler, Mohammed A. Hakami, Abid M. Kareem, Amr M. Khardaly, S. Makkawi, Leena H. Saeed, J. Saeedi, E. Shosha, Mohammad A. Al Jumah
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引用次数: 1

Abstract

For the past 10 years, disease-modifying therapy (DMT) options for multiple sclerosis (MS) have grown remarkably where DMTs have been shown to reduce the risk of MS relapses. MS patients are advised to begin treatment with a DMT shortly after diagnosis to limit the possibility of disease progression over time. While patients with radiologically isolated syndrome do not require pharmacologic treatment, high-risk patients with clinically isolated syndrome are advised to start DMTs. This article provides evidence-based recommendations for DMT use in MS management, helping healthcare practitioners advise patients on treatment decisions. We aim to provide recommendations for the management of acute MS relapses. The recommendations herein were developed following the gathering of a panel of experts after evaluating international guidelines, and the latest evidence was collected through a comprehensive literature review.
关于多发性硬化症管理的沙特共识建议:疾病改善疗法和复发管理
在过去的10年里,多发性硬化症(MS)的疾病修饰疗法(DMT)的选择显著增加,DMT已被证明可以降低MS复发的风险。建议MS患者在诊断后不久开始DMT治疗,以限制疾病随时间进展的可能性。虽然影像学孤立综合征的患者不需要药物治疗,但建议临床孤立综合征的高危患者开始dmt治疗。本文为MS管理中DMT的使用提供了基于证据的建议,帮助医护人员为患者提供治疗决策建议。我们的目的是为急性多发性硬化症复发的管理提供建议。本文中的建议是在评估了国际指南之后,由专家小组组成的,并通过全面的文献综述收集了最新的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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