Ultrasonically-Lubricated Catheters: A Proof of Concept

Mostafa A. Atalla, Jeroen J. Tuijp, Michael Wiertlewski, A. Sakes
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Abstract

Over the past few decades, minimally-invasive en- dovascular interventions have proved its benefits over conventional open heart surgeries, leading to shorter recovery times and lower infection rates. In a typical endovascular procedure, the interventionist inserts a catheter in the radial or femoral artery and navigates it through the arteries to the heart, where the intervention is performed. In order to safely reach the heart, the catheters (and guidewires) used during these procedures need to easily follow the curves in the vascular system, while creating as little friction as possible with the blood vessel wall. If these devices exhibit high friction, there is a risk of damage to the mucous membranes or the intima of the blood vessels, which may lead to infectious diseases or thrombus formation [1], [2]. While low friction is beneficial to avoid damage to the membranes and blood vessel wall, it makes holding a specific location in open spaces, such as inside the heart, difficult. This is particularly true when high forces need to be applied, such as when cutting or puncturing tissues. This suggests the need for new advanced catheters whose frictional properties are controllable and can be adjusted depending on the phase of the catheterization proce- dure; for instance, having low friction while navigating through the vasculature and switching to a high friction state while executing the surgical task. In this work, we propose a novel concept of a variable friction catheter, which comprises discrete modules for friction control. We hereby present the proof-of-concept of the friction control modules, which we characterized in simulation and experimentally. Finally, we present the preliminary results of the sliding friction experiments.
超声润滑导管:概念验证
在过去的几十年里,微创血管内介入手术已经证明了它比传统的心内直视手术更有优势,恢复时间更短,感染率更低。在典型的血管内手术中,介入医生将导管插入桡动脉或股动脉,并通过动脉引导导管到达心脏,在那里进行介入手术。为了安全地到达心脏,在这些过程中使用的导管(和导丝)需要容易地跟随血管系统的曲线,同时尽可能少地与血管壁产生摩擦。如果这些装置具有高摩擦力,则有损伤粘膜或血管内膜的风险,这可能导致传染病或血栓形成。虽然低摩擦有利于避免损伤膜和血管壁,但它使得在开放空间(如心脏内部)保持特定位置变得困难。当需要施加很大的力时尤其如此,例如在切割或穿刺组织时。这表明需要新的先进的导管,其摩擦特性是可控的,可以根据导管过程的阶段进行调整;例如,在导航血管系统时具有低摩擦,在执行手术任务时切换到高摩擦状态。在这项工作中,我们提出了一种可变摩擦导管的新概念,它包括用于摩擦控制的离散模块。在此,我们提出了摩擦控制模块的概念验证,并通过仿真和实验对其进行了表征。最后,给出了滑动摩擦实验的初步结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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