Global Perspective on Understanding the Potential Benefits and Risks of E-Cigarette use on Head and Neck Cancer

Abstract

Head and neck cancer (HNC) is the seventh most common cancer worldwide [1], with 887,659 new cases in 2018 [2]. The time trends in HNC rates from 1983 to 2002 vary by geography [3]. The 2018 age-standardized rate of oral cavity varies from 1.2 per 100,000 in Western Africa to 12.9 in Southeast Asia [2]. The major risk factors are tobacco and alcohol for all HNC subsites, except for HPV infection which is likely the major cause of oropharyngeal cancer in developed countries.