Management of Obesity in Children and Young People

B. White, R. Viner
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Abstract

The management of obesity in childhood and adolescence poses challenges unique to this age group. Compared to adults, obesity-related comorbidities are relatively rare, yet risk factors are increasingly prevalent, frequently undetected, and poorly managed. The evidence base for weight loss interventions and management of comorbidities is limited, with short duration of follow-up only reported, and few randomized controlled trials. Bariatric surgery in adolescents results in the largest magnitude of weight loss, with outcomes similar to those seen in adults. Lifestyle intervention studies have relatively modest outcomes, with unknown long-term outcomes. Only one pharmaceutical agent (orlistat) is licenced in this age group, with generally poor outcomes.
儿童和青少年肥胖的管理
儿童期和青春期肥胖的管理对这一年龄组提出了独特的挑战。与成年人相比,肥胖相关的合并症相对罕见,但危险因素越来越普遍,往往未被发现,管理不善。减肥干预和合并症管理的证据基础有限,只有短时间的随访报道,很少有随机对照试验。青少年减肥手术的减肥效果最大,其结果与成年人相似。生活方式干预研究的结果相对温和,长期结果未知。只有一种药物制剂(奥利司他)被许可用于该年龄组,通常效果较差。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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