Neuronal intermittent synchronization enhanced by astrocytes

S. Makovkin, M. Ivanchenko, S. Gordleeva
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Abstract

In this paper, a study was presented how the interaction of slow modulating astrocytic signaling on fast synaptic transmission between neurons controls fluctuations in the network of hippocampal interneurons that receive input signals from pyramidal cells. The work demonstrates that astrocytic control of signal transmission between neurons improves the synchronization of oscillations and expands the area of synchronization of oscillations in the found parameters of synaptic conduction between synapses of interneurons. The amplification of synaptic transmission caused by astrocytes significantly increases the synchronization of network oscillations in a wide range of parameters of the mathematical model.
星形胶质细胞增强神经元间歇同步
本文研究了星形细胞信号在神经元间快速突触传递中的相互作用如何控制接收锥体细胞输入信号的海马中间神经元网络的波动。研究表明,星形细胞对神经元间信号传递的控制改善了振荡的同步性,扩大了中间神经元突触间突触传导参数的同步振荡范围。星形胶质细胞引起的突触传递放大在数学模型的大范围参数范围内显著增加了网络振荡的同步性。
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