OPTIMIZATION OF ANTIMICROBIAL ACTIVITY OF SYNTHESIZED S-TRIAZINE DERIVATIVES

Abstract

The emergence of new infectious diseases, the resurgence of several infections that appeared to have been controlled and the increase in bacterial resistance have created the necessity for studies directed towards the development of new potential antimicrobials. A series of novel sTriazine has been synthesized and screened for antimicrobial activities. The compound R3 and R10 obtained optimum antibacterial activity against S. aureus; compound R5 obtained optimum antibacterial activity against Pseudomonas aeruginosa and compound R6 obtained optimum antibacterial activity against Bacillus substilis, S. aureus and moderate activity against E. coli and P. aeruginosa at 25ug/ml concentration