Introducing Parallelism in Ribosomal Computing: A Feasibility Study and Analysis

P. Chatterjee, P. Ghosal
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Abstract

Similar to other biomolecular computing, ribosomal computing has been emerged as a promising technology for future generation computing systems. It offers a unique advantage to support the heterogeneity of computing systems with its compatibility with living organisms. This computing imitates the automated process, protein synthesis that translates the input mRNA (messenger RNA) to a protein chain in a ribosome molecule. Multiple ribosomes can translate a single mRNA simultaneously although they work on different codons during this natural procedure. More than one mRNA can also be translated by more than one set of ribosomes. In the proposed work, we use both of these general procedures in our computing environment to induce parallelism. In this paper, two approaches (Approach-I and Approach-II) are proposed to describe the parallel operation techniques. In Approach-I, the input mRNA is subdivided into several mRNA fragments. Each piece is translated by different ribosome molecules simultaneously and suitable to operate on multiple mutually independent inputs. On the other hand, in Approach-II, multiple ribosome molecules can access a single mRNA at a time and use it to execute multiple operations on a single input. Also, it is observed as efficient for mutually dependent operations.
在核糖体计算中引入并行:可行性研究与分析
与其他生物分子计算类似,核糖体计算已成为下一代计算系统的一种有前途的技术。它提供了一个独特的优势,支持计算系统的异构与它的兼容性与生物体。这种计算模拟了蛋白质合成的自动化过程,将输入的mRNA(信使RNA)翻译成核糖体分子中的蛋白质链。多个核糖体可以同时翻译一个mRNA,尽管它们在这个自然过程中作用于不同的密码子。不止一种mRNA也可以被不止一组核糖体翻译。在提出的工作中,我们在我们的计算环境中使用这两种通用过程来诱导并行性。本文提出了两种方法(方法1和方法2)来描述并行运算技术。在approach - 1中,输入mRNA被细分为几个mRNA片段。每个片段由不同的核糖体分子同时翻译,适合在多个相互独立的输入上操作。另一方面,在Approach-II中,多个核糖体分子可以一次访问单个mRNA,并利用它对单个输入执行多个操作。此外,对于相互依赖的操作,它被认为是有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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