Using medication in children’s palliative care

A. Gray, J. Riddin, R. Hain
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Abstract

Using medication in children’s palliative care (CPC) is fraught with difficulties as a result of an insufficient evidence-base and a lack of child friendly formulations, however this cannot be a reason not to intervene and allow unnecessary suffering. A lack of access in some countries to even essential medicines such as opioids is an infringement of the rights of the child to pain relief and needs urgent redress. Often, the only reasonable option is to extrapolate from adult data and to proceed rationally on the basis of what the prescriber knows about the available drug, the individual child, and the likely effects of their disease. Alternative routes for administration of medicines in children who are no longer able to use the oral route, such as the trans- and sub-cutaneous and buccal route mean symptom control can be provided at home and until end of life.
在儿童姑息治疗中使用药物
由于证据不足和缺乏儿童友好型配方,在儿童姑息治疗(CPC)中使用药物充满了困难,但这不能成为不干预和允许不必要痛苦的理由。一些国家甚至无法获得阿片类药物等基本药物,这侵犯了儿童获得缓解疼痛的权利,需要紧急补救。通常,唯一合理的选择是根据成人数据进行推断,并根据开处方者对可用药物、儿童个体及其疾病可能影响的了解进行理性处理。对于不能再使用口服给药途径的儿童,如经和皮下给药途径以及口腔给药途径,意味着可以在家中并直到生命结束时提供症状控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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