Pathophysiological aspects as the object of the treatment tactics in acute pancreatitis (review)

Kryvoruchko Ia, A. Drozdova, N. Goncharova
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Abstract

The review presents a modern view on the features of the course and treatment of acute pancreatitis, based on a cascade of pathophysiological mechanisms of this disease. A number of concepts of development and course of acute pancreatitis on the basis of randomized prospective and retrospective researches devoted to this problem are considered. Attention is paid to the mechanisms of development of organ failure in acute pancreatitis. In accordance with the above, the main positions of treatment measures for acute pancreatitis, which are based on the principles of tactics "step-up approach" were highlighted. Among them, attention is focused on the features of the conservative treatment program, minimally invasive surgical interventions, as well as the management of the postoperative period of patients. Minimally invasive surgical interventions perform the main tasks of surgical treatment in acute pancreatitis, but significantly reduce surgical trauma compared to "open" methods. Adequate management of the postoperative period of patients is carried out through the implementation of protocols "fast-track surgery".
病理生理方面作为急性胰腺炎治疗策略的对象(综述)
本文综述了急性胰腺炎病程特点和治疗的现代观点,基于该疾病的一系列病理生理机制。在随机前瞻性和回顾性研究的基础上,考虑了急性胰腺炎的发展和病程的一些概念。关注急性胰腺炎器官衰竭的发生机制。据此,强调了基于“步步为进”策略原则的急性胰腺炎治疗措施的主要位置。其中,关注的重点是保守治疗方案的特点,微创手术干预,以及患者术后期的管理。微创手术干预是急性胰腺炎手术治疗的主要任务,但与“开放”方法相比,可以显著减少手术创伤。通过实施“快速通道手术”方案,对患者的术后期进行充分的管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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