[The diagnosis of human papillomaviruses in cervical smears by deoxyribonucleic acid hybridization].

Abstract

The method of filter in situ hybridization is applied for diagnostics of human papilloma viruses of the types 11, 16 and 18 in cervical smears [correction of frictions]. The results of the hybridization of 30 cell materials with clonal virus DNA probes proved the existence of human papilloma viruses in 15 patients. The precision of the filter in situ hybridization is demonstrated by comparing the results of the cytological study to the existence of HPV DNA in the same materials proved by in situ DNA hybridization.