Evolution Enhanced Resilience of Protein Interaction Networks

Jiarui Zhang, D. Ding
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Abstract

Most biological functions are presented through protein-protein interaction (PPI) networks. PPI networks show the complex protein-protein interaction relationship within the organism. The generation or destruction of these interaction may lead to changes in biological functions. The latest research results show that the interaction network of species with a higher degree of evolution has higher resilience. Here we explore the resilience changes of a single species during its evolution. We obtain data from public and published websites SNAP. We have proved that no matter what the network structure is, whether it is large or small, when the network fault gradually increases, the resilience gradually decreases. This also indicates that the network with the greatest resilience has a higher degree of evolution.
进化增强了蛋白质相互作用网络的弹性
大多数生物学功能是通过蛋白-蛋白相互作用(PPI)网络实现的。PPI网络显示了生物体内部复杂的蛋白质-蛋白质相互作用关系。这些相互作用的产生或破坏可能导致生物功能的变化。最新的研究结果表明,进化程度越高的物种相互作用网络具有更高的弹性。在这里,我们探讨了单一物种在其进化过程中恢复力的变化。我们从公开和发布的网站SNAP获取数据。我们已经证明,无论网络结构是大是小,当网络故障逐渐增加时,弹性逐渐降低。这也表明弹性最大的网络具有更高的进化程度。
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