Paediatric renal transplantation

Abstract

Indications, procedures, complications, pharmacokinetics and outcomes of renal transplantation are different in children and adults. Subjects <18 years old often have their own list and benefit from donors <15 years old, meaning the waiting time is reduced to <12 months in 71% of cases. Risk of thrombosis limits the use of donors <2 years old and transplantation in children <1 year old. One third of children aged less than 5 years old are transplanted. Living-related transplantation (LRT) is common in the USA (57%) and in Northern Europe, and is often pre-emptive before starting dialysis (24%). The immunosuppressive treatment tends to reduce doses and duration of steroids, optimizing induction therapy Paediatric Renal Transplantation