To Manage Infantile Hypertrophic Pyloric Stenosis by "Double-Y Pyloromyotomy" is a better Surgical Approach

Md. Ansar Ali, K. Hasina, S. Islam, Md. Ashraf Ul Huq, M. Alam, S. Mondal
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Abstract

Background: Different treatment modalities and procedures have been tried for the management of infantile hypertrophic pyloric stenosis. But surgery remains the mainstay for management of IHPS. Ramstedt’s pyloromyotomy was described almost over a hundred years ago and to date remains the surgical technique of choice. An alternative and better technique is the double-Y pyloromyotomy, which offer better results for management of this common condition. Methods: A prospective comparative interventional study of 40 patients with IHPS was carried out over a period of 2 years from July 2008 to July 2010. The patients were divided into 2 equal groups of 20 patients in each. The study was designed that all patients selected for study were optimized preoperatively regarding to hydration, acid-base status and electrolytes imbalance. All surgeries were performed after obtaining informed consent. Standard preoperative preparation and postoperative feeding regimes were used. The patients were operated on an alternate basis, i.e., one patient by Double-Y Pyloromyotomy(DY) and the next by aRamstedt’s Pyloromyotomy (RP). Data on patient demographics, operative time, anesthesia complications, postoperative complications including vomiting and weight gain were collected. Patients were followed up for a period of 3 months postoperatively. Statistical assessments were done by using t test. Results: From July 2008 through July 2010, fourty patients were finally analyzed for this study. Any statistical differences were observed in patient population regarding age, sex, weight at presentation, symptoms and clinical condition including electrolytes imbalance and acid-base status were recorded. Significant differences were found in postoperative vomiting and weight gain. Data of post operative vomiting and weight gain in both groups were collected. Vomiting in double-Y(DY) pyloromyotomy group (1.21 ± 0.45days) vs Ramstedt’s pyloromyotomy (RP) group(3.03 ± 0.37days) p= 0.0001.Weight gain after 1st 10 days DY vs RP is ( 298 ± 57.94 gm vs193±19.8 gm p=0.0014), after 1 month (676.67±149.84 gm vs 466.67 ± 127.71 gm, p=0.0001), after 2months (741.33± 278.74 gm vs 490±80.62 gm, p=0.002) and after 3 months (582±36.01gm vs 453.33±51.64 gm, p=0.0001).No long-term complications were reported and no re-do yloromyotomy was needed. Conclusion: The double-Y pyloromyotomy seems to be a better technique for the surgical management of IHPS. It may offer a better functional outcome in term of postoperative vomiting and weight gain. DOI: http://dx.doi.org/10.3329/jpsb.v1i2.19532
双y型幽门肌切开术治疗婴儿肥厚性幽门狭窄是一种较好的手术方法
背景:不同的治疗方式和程序已经尝试了治疗婴儿肥厚性幽门狭窄。但是手术仍然是治疗IHPS的主要方法。Ramstedt的幽门肌切开术早在100多年前就已被描述,至今仍是首选的手术技术。另一种更好的方法是双y型幽门切开术,它对治疗这种常见疾病有更好的效果。方法:2008年7月至2010年7月对40例IHPS患者进行前瞻性比较介入研究。将患者分为2组,每组20例。本研究的设计是,所有入选研究的患者术前均对水合作用、酸碱状态和电解质失衡进行了优化。所有手术均在获得知情同意后进行。采用标准的术前准备和术后喂养方案。患者采用双y型幽门肌切开术(DY)和aRamstedt型幽门肌切开术(RP)交替手术。收集患者人口统计学数据、手术时间、麻醉并发症、术后并发症包括呕吐和体重增加。术后随访3个月。统计学评价采用t检验。结果:从2008年7月到2010年7月,最终分析了40例患者。在年龄、性别、就诊时体重、症状和临床状况(包括电解质失衡和酸碱状态)方面观察到患者人群的统计学差异。在术后呕吐和体重增加方面存在显著差异。收集两组患者术后呕吐及体重增加情况。双y型(DY)幽门肌切开术组呕吐(1.21±0.45天)vs Ramstedt幽门肌切开术组呕吐(3.03±0.37天)p= 0.0001。1个月后(676.67±149.84 gm vs 466.67±127.71 gm, p=0.0001), 2个月后(741.33±278.74 gm vs 490±80.62 gm, p=0.002), 3个月后(582±36.01gm vs 453.33±51.64 gm, p=0.0001)体重增加(298±57.94 gm vs193±19.8 gm, p=0.0014)。无长期并发症报道,无需再次做子宫肌瘤切开术。结论:双y型幽门肌切开术是治疗IHPS的较好方法。就术后呕吐和体重增加而言,它可能提供更好的功能结果。DOI: http://dx.doi.org/10.3329/jpsb.v1i2.19532
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