Chinese Version of VEINES-QOL/Sym Questionnaire in Chinese Patients with Deep Venous Thrombosis: Cultural Adaptation and Psychometric Properties

Abstract

Purpose:To verify the psychometrical properties of the Chinese-version VEnous INsufficiency Epidemiological and Economic Study-Quality of Life/Symptoms (VEINES-QOL/Sym) questionnaire, in Chinese patients with deep venous thrombosis.Methods:The English-version VEINES-QOL/Sym questionnaire was translated into Chinese by forward-translation, back-translation and cultural adjustment, and approved by the original authors. It was administered to patients with deep venous thrombosis of the two local hospitals in Nanchong from Jul 2017 to Jan 2018. The internal consistency reliability and construct validity of the Chinese version of VEINES-QOL/Sym questionnaire were evaluated. Main outcome measures were as follows: Reliability was tested using Cronbach’s alpha coefficient, internal consistency reliability, retest reliability, split-half reliability . Validity was verified by structure validity, content validity and criterion-related validity.Results:In pilot study, a total of 132 participates completed the questionnaire. In validity sample, a total of 335 participates completed the questionnaire. The Chinese-version VEINES-QOL/Sym questionnaire has 25 items. And it had good internal consistency and stability (Cronbach’s α coefficients ranging from 0.877-0.930, split-half coefficients ranging from 0.792-0.913 and retest coefficients ranging from 0.891-0.987). The Chinese-version VEINES-QOL/Sym summary score had good criterion-related validity in the PCS (physical component summary) and MCS (mental component summary) of Chinese-version SF-36 (0.801 and 0.792). Four factors emerged from exploratory factor analysis, which named symptoms (Q1a-i, Q6), physical functioning (Q2, Q3a-d), role-physical (Q4a-d, Q5) and mental health (Q7a-e) respectively. ConclusionsThis questionnaire was shown to be reliable and valid in the Chinese language. We propose that the Chinese-version VEINES-QOL/Sym is a useful tool for local use.