Holistic Herbs – A Natural Aresnal for Contention between Bugs and Drugs

Abstract

Nosocomial infections are one of the major causes of disease globally, leading to the most frequent adverse events in healthcare setups worldwide [1]. Millions of patients are affected by nosocomial infections each year globally, bringing about significant mortality and economic losses in healthcare systems. At any given time, the prevalence of health care-associated infections in developed countries varies between 3% to 15% [2]. Moreover, nosocomial infections are becoming even more complicated to treat as antibiotic resistance surfaces up. Recent reports from Centre for Disease Control (CDC) and World Health Organization (WHO) have indicated that nosocomial infections accounts for approximately 2 million infections and 90,000 deaths per year, out of which nearly 23% deaths are attributed to reemerging antibiotic resistant pathogens [3]. Antibiotics comprising bactericidal or bacteriostatic chemotherapeutic agents are presently the only available therapeutic option for the management and deterrence of infectious diseases. However, several drug resistant microbes are emerging as a result of continuous mutations, there by restraining the efficacy of such pharmaceuticals [4]. Over use of antibiotics imposes selective pressure on a specific population of bacteria, thereby allowing the resistant bacteria to thrive and the susceptible bacteria to die off[5].