Unsatisfactory LDL-cholesterol Goal Attainment Rate in Type 2 Diabetic Patients

Yung-Sheng Chang, M. Hsieh
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Abstract

Background: Type 2 diabetic patients have a higher cardiovascular risk than people without diabetes, and tight lipid level control is recommended to reduce the cardiovascular risk. We attempted to examine the factors associated with the low-density lipoprotein-cholesterol (LDL-C) control attainment rate and the actual LDL-C control attainment rate in type 2 diabetic patients in Taiwan. Methods: This cross-sectional study of LDL-C control in type 2 diabetic patients collected data from 10,000 patients. The LDL-C goal was < 100 mg/dL for all diabetic patients. Multivariate logistic regression was performed to evaluate factors associated with the attainment rate of LDL-C control. Results: 46.63% of the diabetic patients attained the LDL-C goal. Young and female patients were less successful in reaching the LDL-C goal than other participants. 51.07% of the type 2 diabetic patients with cardiovascular comorbidities attained an LDL-C < 100 mg/dL, and nearly 11% of those patients attained an LDL-C < 70 mg/dL. Conclusions: The LDL-C goal attainment rate in type 2 diabetic patients is unsatisfactory in clinical practice, especially in patients with cardiovascular comorbidities. Young and female patients had a lower attainment rate than other participants.
2型糖尿病患者低密度脂蛋白胆固醇目标完成率
背景:2型糖尿病患者的心血管风险高于非糖尿病患者,建议严格控制血脂水平以降低心血管风险。本研究旨在探讨台湾地区2型糖尿病患者低密度脂蛋白胆固醇(LDL-C)控制完成率及实际LDL-C控制完成率的相关因素。方法:2型糖尿病患者LDL-C控制的横断面研究收集了10,000例患者的数据。所有糖尿病患者的LDL-C目标均< 100 mg/dL。采用多因素logistic回归评价与LDL-C控制达标率相关的因素。结果:46.63%的糖尿病患者LDL-C达标。与其他参与者相比,年轻和女性患者达到LDL-C目标的成功率较低。51.07%伴有心血管合并症的2型糖尿病患者LDL-C < 100mg /dL,其中近11%的患者LDL-C < 70mg /dL。结论:临床上2型糖尿病患者LDL-C目标完成率不理想,特别是合并心血管疾病的患者。年轻和女性患者的获得率低于其他参与者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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