Beta-2-microglobulin release in mixed lymphocyte cultures.

Abstract

Significantly more beta 2-m is released in MLCs than in control cultures of cells from one donor or in cultures of pooled irradiated cells from several donors. Beta 2-m release increases with cultivation time and depends on the intensity of stimulation. It is highest in three-way MLCs and lowest in one-way MLCs when cells of haploidentical individuals are cocultivated.