Phytochemicals and acetylcholinesterase activity of stem bark daniella oliveri ethyl acetate extract

Abstract

Before the coming of modern drugs circulating now all over the world, traditional plants were in existence. The parts of the plants mostly used are root, stem bark, stem, flower, fruits and seed are ingredients of orthodox medicines. The components of phytochemical signify the healing value of plants. Phytochemical performs physiological activities on the human system; some of the significant phytochemical are flavonoids, alkaloids, phenolic and tannins compounds. In this research, the GC-MS of Daniella Oliveri ethyl acetate stem bark extract revealed 49 bioactive components, δ-cadinene and ϒ-Muurolene, having the highest percentage among other antioxidant compounds. The acetylcholinesterase (AChE) donepezil used to examine the inhibition activity shows a linear progression with the D. Oliveri extracts. Even though there is extensive information on the ethnopharmacological uses of D. Oliveri, there is a shortage of scientific reports on the anti-fungal properties of the plant, therefore, this study aimed at evaluating the biochemical compositions of the plant in order to ascertain its ethnomedicinal use in the treatment of skin ailments and others diseases.