Attaining specificity in the measurement of ethanol in breath.

Acta medicinae legalis et socialis Pub Date : 1990-01-01
C M Bell
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Abstract

In most cases, new breath alcohol measuring devices satisfy the requirements for accuracy and precision. All instruments however, have responded to some substances other than ethanol. In this area of instruments specificity for ethanol there is scope for further development. Substances other than ethanol may be distinguished as interfering substances by the use of two methods of ethanol detection. One example of this is dual-wavelength infra-red detection. Alternatively, infra-red detection could be coupled to a fuel-cell or Taguchi cell detector. Comparison of the two readings obtained should allow most substances other than ethanol to be distinguished as interfering substances. Two instruments using two modes of ethanol detection are the Intoximeter 3000 (3.4 um infra-red plus Taguchi cell) and the BAC DataMaster (dual wavelength infra-red). These have proved unsuitable because of incomplete specificity for ethanol, largely because acetone appears to be considered the only potential interfering substance. In the selection of two modes of ethanol detection, each system must be chosen such that a comparison of the response from each mode would indicate a wide range of possible interfering substances, not just acetone. A performance specification has been developed, against which future commercial instruments will be evaluated.

获得呼吸中乙醇测量的特异性。
在大多数情况下,新的呼气酒精测量装置可以满足准确度和精密度的要求。然而,所有的仪器都对乙醇以外的一些物质有反应。在乙醇专用仪器的这一领域有进一步发展的余地。乙醇以外的物质可以通过使用两种乙醇检测方法来区分为干扰物质。其中一个例子是双波长红外探测。另外,红外探测可以与燃料电池或田口电池探测器相结合。将所获得的两个读数进行比较,应该可以将除乙醇以外的大多数物质区分为干扰物质。使用两种模式乙醇检测的两种仪器是Intoximeter 3000 (3.4 um红外线加田口细胞)和BAC DataMaster(双波长红外线)。这些方法被证明是不合适的,因为乙醇的特异性不完全,主要是因为丙酮似乎被认为是唯一潜在的干扰物质。在选择乙醇检测的两种模式时,每种系统的选择必须使每种模式的响应的比较能够表明广泛的可能的干扰物质,而不仅仅是丙酮。已经制定了性能规范,未来的商业仪器将据此进行评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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