[Permanence of chlamydia in trachomatous tissue].

P Verin, P Gendre, H Andrianjafy, B Mortemousque
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Abstract

Electron-microscopic examination of conjunctival and corneal biopsies from six apparently healed trachomatous patients demonstrated chlamydiae in situ. Nine previously trachomatous patients were submitted to the same biopsies; all biopsies were positives. After two months specific anti-chlamydial treatment, we observed the same result before anterior segment surgery. Nevertheless surgery was performed without consequences except for the two corneal grafts which failed. We must ask for two questions: how long chlamydial particles persist in trachomatous tissue? What is the real efficacy of topical anti-chlamydial drugs?

沙眼组织中衣原体的持久性。
6例明显愈合的沙眼患者的结膜和角膜活检电镜检查显示有原位衣原体。9例既往沙眼患者接受相同的活组织检查;所有活检结果均为阳性。经过两个月的特异性抗衣原体治疗后,我们观察到与前段手术前相同的结果。尽管如此,除了两个角膜移植失败外,手术没有任何后果。我们必须提出两个问题:衣原体颗粒在沙眼组织中存在多久?局部抗衣原体药物的真正功效是什么?
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