Significance of 5 alpha-androstane-3 alpha, 17 beta-diol in submandibular gland.

M Tarui, S Koshika, T Nishimura, T Yoneda, Y Nakayama
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Abstract

5 alpha-Androstane-3 alpha, 17 beta-diol (3 alpha-diol) was measured in the submandibular gland (SMG) of male and female rats by radioimmunoassay (RIA) at 4 and 7 weeks of age. The raised and constant concentration of 3 alpha-diol was revealed in female SMG. The mean values of 3 alpha-diol in female SMG were found to be significantly higher than testosterone (T) and dihydrotestosterone (DHT). 3 alpha-diol in male SMG was similar to that of DHT and these two steroids decreased by the 7th week.

5 α -雄烷-3 α, 17 β -二醇在颌下腺中的意义。
采用放射免疫法(RIA)测定4、7周龄雄性和雌性大鼠颌下腺(SMG)中5 α -雄甾烷-3 α, 17 β -二醇(3 α -二醇)含量。3 -二醇在雌性SMG中呈升高和稳定的状态。女性SMG中3 α -二醇的平均值明显高于睾酮(T)和二氢睾酮(DHT)。3 α -二醇在男性SMG中与DHT相似,这两种类固醇在第7周下降。
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