HbA1c Reduction in Diabetic Older Blacks and Hispanics: A Study on Mobile Physical Activity Tracking

Helen Z Wu, G. Ruaño, Biju Wang, J. Grady, Marsha M. Murray, Michelle Slivinsky, C. Laurencin
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Abstract

ABSTRACT Introduction/Purpose Diabetes is a leading cause of morbidity and mortality and is more prevalent in Blacks and Hispanics. This study aims to examine if different physical activity (PA) intensities reduced hemoglobin A1c (HbA1c) in Blacks and Hispanics with type 2 diabetes mellitus (DM2). Methods This pilot study used a one-sample pre- and postintervention design, including four in-person visits during a period of 3 months from January 2018 to December 2020 in Black or Hispanic populations with DM2 in the Greater Hartford, Connecticut, area. At each in-person visit HbA1c; specific, measurable, achievable, realistic, and time-bound goals; and daily PA (categorized into high-, moderate-, or low-intensity levels by a Fitbit® Charge 2) were obtained. Change scores for minutes engaged in each PA level and HbA1c values were created between visits. A linear mixed model was used to analyze these relationships over time. Results Among 17 completed participants, mean age was 56 yr, 11 were Black, 6 were Hispanic, 13 were female, and 4 were male. At baseline, mean body mass index was 34.8 kg·m−2 and mean systolic/diastolic blood pressure was 135/81 mm Hg. From 70.2 mmol·mol−1 at baseline, HbA1c decreased to 66.3 after 4 wk, 66.0 after 8 wk, and 63.5 by 12 wk (9.5% reduction, P < 0.05). Average daily PA time increased over 3 months from 15.8 to 20.3 (P = 0.04) to 20.8 (P = 0.02) minutes for moderate-intensity PA (P = 0.05), and from 12.1 to 13.6 (P = 0.08) to 15.2 (P = 0.01) minutes for high-intensity PA. PA increases were significantly associated with an overall 0.58% reduction of HbA1c (P = 0.04). Conclusion Guided by carefully selected, evidenced-based behavioral change strategies, this study found that increases of ~7 min of moderate- or high-intensity daily PA were associated with ~10% decrease in HbA1c in Blacks and Hispanics with DM2. This is consistent with the current consensus statement from the American College of Sports Medicine.
糖尿病老年黑人和西班牙裔患者HbA1c降低:一项移动体育活动追踪研究
糖尿病是发病率和死亡率的主要原因,在黑人和西班牙裔人群中更为普遍。本研究旨在研究不同体力活动(PA)强度是否会降低黑人和西班牙裔2型糖尿病(DM2)患者的血红蛋白A1c (HbA1c)。该试点研究采用单样本干预前和干预后设计,包括在2018年1月至2020年12月的3个月内,对康涅狄格州大哈特福德地区患有DM2的黑人或西班牙裔人群进行四次亲自访问。每次上门检查时的糖化血红蛋白;具体的、可衡量的、可实现的、现实的、有时间限制的目标;以及每日PA(通过Fitbit®Charge 2分为高、中、低强度水平)。在两次访问之间创建每个PA水平的分钟变化分数和HbA1c值。一个线性混合模型被用来分析这些随时间的关系。结果在17名完成的参与者中,平均年龄为56岁,11名黑人,6名西班牙裔,13名女性,4名男性。基线时,平均体重指数为34.8 kg·m−2,平均收缩压/舒张压为135/81 mm Hg, HbA1c从基线时的70.2 mmol·mol−1降至4周后的66.3,8周后的66.0,12周后的63.5(降低9.5%,P < 0.05)。中等强度PA从15.8 ~ 20.3 (P = 0.04)分钟增加到20.8 (P = 0.02)分钟(P = 0.05),高强度PA从12.1 ~ 13.6 (P = 0.08) ~ 15.2 (P = 0.01)分钟。PA升高与HbA1c总体降低0.58%显著相关(P = 0.04)。结论:在精心选择的、以证据为基础的行为改变策略的指导下,本研究发现,患有DM2的黑人和西班牙裔患者每日增加~7分钟的中等或高强度PA可使HbA1c降低~10%。这与美国运动医学学院目前的共识一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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